Vascularized Tissue Constructs
نویسندگان
چکیده
A major challenge in tissue engineering is the lack of proper vascularization of the fabricated tissue constructs. Microscale technologies, especially microfluidic systems, provide new opportunities to overcome the challenge of developing artificial micro-vasculatures. In this chapter, the application of microfluidic systems for generating vascularized tissue constructs by using microfluidic platforms has been outlined. Mathematical modeling has been shown as a powerful tool for optimizing the microfluidic system design parameters. Future challenges for the microfluidic-based tissue engineering constructs have also been discussed for success in clinical application. 7 Microfluidic Systems for Engineering Vascularized Tissue Constructs 3
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